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editing\uff09\u7642\u6cd5\uff0c\u5c6c\u6539\u826f\u81eaCRISPR\u7684\u65b0\u578b\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u800c\u91ab\u751f\u5c31\u99ac\u723e\u767b\u7684\u75c5\u60c5\u300c\u5ea6\u8eab\u8a02\u505a\u300d\u6cbb\u7642\u65b9\u6848\u3002<\/p>\n<p>\u8cd3\u5915\u6cd5\u5c3c\u4e9e\u5927\u5b78\u57fa\u56e0\u7de8\u8f2f\u5c08\u5bb6\u7a46\u8607\u52aa\u9b6f\uff08Kiran Musunuru\uff09\u53bb\u5e748\u6708\u6536\u5230\u8cbb\u57ce\u5152\u7ae5\u91ab\u9662\u7684\u91ab\u751f\u963f\u502b\u65af-\u5c3c\u514b\u62c9\u65af\uff08Rebecca Ahrens-Nicklas\uff09\u96fb\u90f5\u63d0\u53ca\u99ac\u723e\u767b\u7684\u75c5\u60c5\u3002\u7a46\u8607\u52aa\u9b6f\u4e00\u76f4\u90fd\u7814\u7a76\u7528\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\u6cbb\u7642\u5e38\u898b\u57fa\u56e0\u7a81\u8b8a\uff0c\u800c\u70ba\u99ac\u723e\u767b\u7279\u88fd\u4e26\u6e2c\u8a66\u6cbb\u7642\u65b9\u6848\u4e26\u4e0d\u5bb9\u6613\uff1a\u5728\u7d93\u6b77\u7a46\u8607\u52aa\u9b6f\u8207\u5176\u4ed6\u5b78\u8005\u53ca\u4f01\u696d\u5408\u4f5c\uff0c\u7d42\u70ba\u7537\u5b30\u300c\u5ea6\u8eab\u8a02\u505a\u300d\u51fa\u7642\u6cd5\u3002<\/p>\n<h2>\u975c\u8108\u6ce8\u5c04\u57fa\u56e0\u300c\u6307\u4ee4\u300d\u300c\u5b9a\u4f4d\u300d\u8102\u8cea<\/h2>\n<p>\u7537\u5b302\u6708\u63a5\u53d7\u4e86\u9996\u6b21\u975c\u8108\u6ce8\u5c04\uff0c\u5c07\u5305\u88f9\u7740\u7642\u6cd5\u6240\u9700\u57fa\u56e0\u7de8\u8f2f\u300c\u6307\u4ee4\u300d\u548c\u5206\u5b50\u300c\u5b9a\u4f4d\u7cfb\u7d71\u300d\uff08CRISPR\uff09\u7684\u8102\u8cea\u7d0d\u7c73\u7c92\u5b50\u9001\u5165\u9ad4\u5167\u3002\u9019\u4e9b\u8102\u8cea\u80fd\u88ab\u809d\u7d30\u80de\u5438\u6536\uff0c\u5c07\u57fa\u56e0\u7de8\u8f2f\u6210\u5206\u7cbe\u6e96\u8f38\u9001\u81f3\u76ee\u6a19\u90e8\u4f4d\u3002\u7537\u5b30\u57283\u6708\u82074\u6708\u63a5\u53d7\u5f8c\u7e8c\u5291\u91cf\u6cbb\u7642\u5f8c\uff0c\u72c0\u6cc1\u986f\u8457\u6539\u5584\uff0c\u73fe\u5728\u9032\u98df\u8f03\u70ba\u6b63\u5e38\uff0c\u4e26\u4e14\u5728\u9762\u5c0d\u5982\u611f\u5192\u9019\u985e\u6703\u5c0d\u8eab\u9ad4\u9020\u6210\u8ca0\u64d4\u3001\u52a0\u5287CPS1\u75c7\u72c0\u7684\u5e38\u898b\u75be\u75c5\u6642\uff0c\u4e5f\u80fd\u8f03\u9806\u5229\u5eb7\u5fa9\u3002\u6b64\u5916\uff0c\u9019\u4f4d\u73fe\u5e749\u500b\u534a\u6708\u5927\u7684\u5b30\u5152\u76ee\u524d\u6240\u9700\u670d\u7528\u7684\u85e5\u7269\u4e5f\u5df2\u6e1b\u5c11\u3002\u91ab\u7642\u5718\u968a\u8a08\u5283\u8b93\u4ed6\u51fa\u9662\u56de\u5bb6\u3002\u7537\u5b30\u7684\u9ad4\u91cd\u73fe\u5728\u8655\u65bc\u540c\u9f61\u5b30\u5152\u768440%\uff0c\u672a\u77e5\u4ed6\u672a\u4f86\u662f\u5426\u53ef\u514d\u65bc\u809d\u81df\u79fb\u690d\u3002<\/p>\n<h2>\u91ab\u7642\u5718\u968a\u7a31\u9700\u6642\u89c0\u5bdf 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Urnov\uff09\u8868\u793a\uff0c\u5982\u6b64\u5feb\u901f\u751f\u7522\u7528\u65bc\u6cbb\u7642\u907a\u50b3\u75be\u75c5\u7684\u81e8\u7240\u7d1aCRISPR\uff0c\u5728\u4ed6\u5011\u9019\u9818\u57df\u4e0a\u662f\u53f2\u7121\u524d\u4f8b\u3002<\/p>\n<p>\u963f\u502b\u65af-\u5c3c\u514b\u62c9\u65af\u8868\u793a\u9019\u4e00\u7a81\u7834\u5f97\u76ca\u65bc\u57fa\u56e0\u7de8\u8f2f\u9818\u57df\u7684\u591a\u5e74\u9032\u6b65\uff0c\u6307\uff1a\u300cKJ\uff08\u99ac\u723e\u767b\uff09\u53ea\u662f\u4e00\u540d\u60a3\u8005\uff0c\u4f46\u6211\u5011\u5e0c\u671b\u4ed6\u662f\u773e\u591a\u53d7\u76ca\u8005\u4e2d\u7684\u9996\u500b\u3002\u300d\u7a46\u8607\u52aa\u9b6f\u4ea6\u8868\u793a\uff1a\u300c\u6211\u5011\u6578\u5341\u5e74\u4f86\u807d\u805e\u7684\u57fa\u56e0\u6cbb\u7642\u524d\u666f\u5373\u5c07\u5be6\u73fe\uff0c\u5b83\u5c07\u5fb9\u5e95\u6539\u8b8a\u6211\u5011\u5c0d\u91ab\u5b78\u7684\u61c9\u7528\u65b9\u5f0f\u3002\u300d<\/p>\n<\/div>\n<\/div>\n<div 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